Lausanne cohort 65+ (Lc65+) study

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The Lausanne cohort 65+ (Lc65+) study is a research platform that aims to gain new knowledge on frailty in the general population from the age of 65 years onwards. Manifestations of frailty, medical and psycho-social risk factors, and the effects of frailty on health, functional status, and use of health services are central to the research conducted in the Lc65+ project.

The Lc65+ study was launched in 2004 at the  Institute of Social and Preventive Medicine (IUMSP) of the Lausanne University Hospital Center (CHUV). The cohort is based on a representative sample of residents of the city of Lausanne (canton Vaud, Switzerland, 120’000 inhabitants) born before, during, and after World War II.

The long term goals of this public health project are improvements in the quality of life of older persons by preventing frailty and its adverse effects early.

The main objectives



To compare health evolution and health care service utilization from age 65 onwards in three consecutive samples issued from the general population



To improve our understanding of the frailty process and its consequences, as well as related needs for care, based on longitudinal data


To design preventive interventions aimed at avoiding or delaying unfavorable outcomes in older age



La cohorte Lc65+

L'étude Lausanne cohorte 65+ (Lc65+) est une plate-forme de recherche sur le vieillissement visant à mieux connaître la fragilité dès l’âge de 65 ans au niveau d’une population générale.

Les travaux d'analyse sont centrés sur les manifestations de la fragilité, ses facteurs de risque médicaux et psychosociaux, ainsi que sur ses effets sur la santé, l'autonomie fonctionnelle et le recours aux services de santé.

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